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Employer: Thomas Jefferson University (TJU)
Location: United States
Publication date: 13 Sep 2017
A postdoctoral position is available in the laboratory of Dr. Sophie Astrof at Thomas Jefferson University to study roles of cell-extracellular matrix (ECM) interactions in cardiovascular development and congenital heart disease. We have recently discovered that progenitors within the second heart field (SHF) give rise to endothelial cells composing pharyngeal arch arteries. Projects in the lab focus on the role of ECM in regulating the development of SHF-derived progenitors into endothelial cells and their morphogenesis into blood vessels. The successful candidate will combine genetic manipulation, embryology, cell biology, and confocal imaging to study molecular mechanisms of microenvironmental sensing during vascular development. Astrof laboratory is a part of a modern and well-equipped Center for Translational Medicine at Jefferson Medical College [link to] located in the heart of Philadelphia. For further information on our work, please see the following publications: Wang et al., Development, 143:88-100, 2016 and Wang et al, Developmental Biology 421:108-217, 2017. To apply, please send a letter of interest detailing your expertise, CV and names and contact information of three references to [link to] an employer, Jefferson maintains a commitment to provide equal access to employment.  Jefferson values diversity and encourages applications from women, members of minority groups, LGBTQ individuals, disabled individuals, and veterans.    
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