Postdoctoral Research Scientist

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Employer: The Mortimer B. Zuckerman Mind Brain Behavior Institute
Location: United States
Publication date: 14 Sep 2017
Description:
Postdoctoral opportunities at the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University in the City of New York, USA The Fitzpatrick lab, a member of the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University in the City of New York (https://zuckermaninstitute.columbia.edu/), has openings for four (4) postdoctoral scientists opportunities. Situated in the heart of Manhattan, at full capacity the Zuckerman Institute will house nearly sixty laboratories employing a broad range of interdisciplinary approaches to transform our understanding of the mind and brain. In this highly collaborative environment, labs work together to gain critical insights into human health by exploring how the brain develops, performs, endures and recovers from trauma or disease. In our lab, we leverage the latest developments in cryo-electron microscopy with complementary biophysical techniques (proteomics, light-microscopy, microfluidics) to explore the molecular basis of neurodegeneration (e.g. PNAS 110, 5468-5473 and Nature 547, 185-190). To this end, we determine the structure and function of protein complexes, purified directly from postmortem brain tissue, that are implicated in a range of neurodegenerative diseases. Additionally, we will visualize the behavior of these complexes within the cellular context using light-microscopy and cryo-electron tomography. We are looking for outstanding scientists who have a strong background in biophysics, biochemistry or neuroscience, and are highly motivated to learn single-particle cryo- EM. Prior experience with single-particle cryo-EM or X-ray crystallography is considered an advantage, but is not essential. If you’re interested in joining our lab, please send your CV with a brief description of your current research, as well as 2-3 contacts for references, to [link to Naturejobs.com] before the 31st of October, 2017. Columbia University is an Affirmative Action/Equal Opportunity employer. Columbia values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected veterans, and underrepresented minorities.
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